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Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells

Members of the bromodomain and extra-C terminal (BET) domain protein family and the histone deacetylase (HDAC) enzyme family regulate the expression of important oncogenes and tumor suppressor genes. Here we show that the BET inhibitor JQ1 inhibits proliferation and induces apoptosis of both triple...

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Detalles Bibliográficos
Autores principales: Borbely, Gabor, Haldosen, Lars-Arne, Dahlman-Wright, Karin, Zhao, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741790/
https://www.ncbi.nlm.nih.gov/pubmed/26378038