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Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies
Olfactory dysfunction is present in up to 90% of Alzheimer's disease (AD) patients. Although deposition of hyperphosphorylated tau and β-amyloid substrates are present in olfactory areas, the molecular mechanisms associated with decreased smell function are not completely understood. We have ap...
Autores principales: | Zelaya, María Victoria, Pérez-Valderrama, Estela, de Morentin, Xabier Martínez, Tuñon, Teresa, Ferrer, Isidro, Luquin, María Rosario, Fernandez-Irigoyen, Joaquín, Santamaría, Enrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741837/ https://www.ncbi.nlm.nih.gov/pubmed/26517091 |
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