Systematic evaluation of underlying defects in DNA repair as an approach to case-only assessment of familial prostate cancer

Risk assessment for prostate cancer is challenging due to its genetic heterogeneity. In this study, our goal was to develop an operational framework to select and evaluate gene variants that may contribute to familial prostate cancer risk. Drawing on orthogonal sources, we developed a candidate list...

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Detalles Bibliográficos
Autores principales: Nicolas, Emmanuelle, Arora, Sanjeevani, Zhou, Yan, Serebriiskii, Ilya G., Andrake, Mark D., Handorf, Elizabeth D., Bodian, Dale L., Vockley, Joseph G., Dunbrack, Roland L., Ross, Eric A., Egleston, Brian L., Hall, Michael J., Golemis, Erica A., Giri, Veda N., Daly, Mary B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741850/
https://www.ncbi.nlm.nih.gov/pubmed/26485759

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