INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

Inositol polyphosphate 4-phosphatase type II (INPP4B) negatively regulates PI3K/Akt signalling and has a tumour suppressive role in some types of cancers. However, we have found that it is upregulated in a subset of melanomas. Here we report that INPP4B can function as an oncogenic driver through ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Chi, Meng Na, Guo, Su Tang, Wilmott, James S., Guo, Xiang Yun, Yan, Xu Guang, Wang, Chun Yan, Liu, Xiao Ying, Jin, Lei, Tseng, Hsin-Yi, Liu, Tao, Croft, Amanda, Hondermarck, Hubert, Scolyer, Richard A., Jiang, Chen Chen, Zhang, Xu Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741868/
https://www.ncbi.nlm.nih.gov/pubmed/26573229

Ejemplares similares

Ejemplares similares