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Key contribution of eIF4H-mediated translational control in tumor promotion

Dysregulated expression of translation initiation factors has been associated with carcinogenesis, but underlying mechanisms remains to be fully understood. Here we show that eIF4H (eukaryotic translation initiation factor 4H), an activator of the RNA helicase eIF4A, is overexpressed in lung carcino...

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Detalles Bibliográficos
Autores principales: Vaysse, Charlotte, Philippe, Céline, Martineau, Yvan, Quelen, Cathy, Hieblot, Corinne, Renaud, Claire, Nicaise, Yvan, Desquesnes, Aurore, Pannese, Maria, Filleron, Thomas, Escourrou, Ghislaine, Lawson, Malcolm, Rintoul, Robert C., Delisle, Marie Bernadette, Pyronnet, Stéphane, Brousset, Pierre, Prats, Hervé, Touriol, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741870/
https://www.ncbi.nlm.nih.gov/pubmed/26498689