Sorafenib-induced defective autophagy promotes cell death by necroptosis

Autophagy is one of the main cytoprotective mechanisms that cancer cells deploy to withstand the cytotoxic stress and survive the lethal damage induced by anti-cancer drugs. However, under specific conditions, autophagy may, directly or indirectly, induce cell death. In our study, treatment of the A...

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Detalles Bibliográficos
Autores principales: Kharaziha, Pedram, Chioureas, Dimitris, Baltatzis, George, Fonseca, Pedro, Rodriguez, Patricia, Gogvadze, Vladimir, Lennartsson, Lena, Björklund, Ann-Charlotte, Zhivotovsky, Boris, Grandér, Dan, Egevad, Lars, Nilsson, Sten, Panaretakis, Theocharis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research paper: Autophagy and Cell Death
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741916/
https://www.ncbi.nlm.nih.gov/pubmed/26416459

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