Cargando…

MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients

Patients with primary HER2-positive breast cancer benefit from HER2-targeted therapies. Nevertheless, a significant proportion of these patients die of disease progression due to mechanisms of drug resistance. MicroRNAs (miRNAs) are emerging as critical core regulators of drug resistance that act by...

Descripción completa

Detalles Bibliográficos
Autores principales: De Mattos-Arruda, Leticia, Bottai, Giulia, Nuciforo, Paolo G., Di Tommaso, Luca, Giovannetti, Elisa, Peg, Vicente, Losurdo, Agnese, Pérez-Garcia, José, Masci, Giovanna, Corsi, Fabio, Cortés, Javier, Seoane, Joan, Calin, George A., Santarpia, Libero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741929/
https://www.ncbi.nlm.nih.gov/pubmed/26452030

Ejemplares similares