Arsenic trioxide disrupts glioma stem cells via promoting PML degradation to inhibit tumor growth

Glioblastoma multiforme (GBM) is the most lethal brain tumor. Tumor relapse in GBM is inevitable despite maximal therapeutic interventions. Glioma stem cells (GSCs) have been found to be critical players in therapeutic resistance and tumor recurrence. Therapeutic drugs targeting GSCs may significant...

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Detalles Bibliográficos
Autores principales: Zhou, Wenchao, Cheng, Lin, Shi, Yu, Ke, Susan Q., Huang, Zhi, Fang, Xiaoguang, Chu, Cheng-wei, Xie, Qi, Bian, Xiu-wu, Rich, Jeremy N., Bao, Shideng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741931/
https://www.ncbi.nlm.nih.gov/pubmed/26510911

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