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Silencing of E2F3 suppresses tumor growth of Her2(+) breast cancer cells by restricting mitosis

The E2F transcriptional activators E2F1, E2F2 and E2F3a regulate many important cellular processes, including DNA replication, apoptosis and centrosome duplication. Previously, we demonstrated that silencing E2F1 or E2F3 suppresses centrosome amplification (CA) and chromosome instability (CIN) in He...

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Detalles Bibliográficos
Autores principales:	Lee, Miyoung, Oprea-Ilies, Gabriela, Saavedra, Harold I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741932/ https://www.ncbi.nlm.nih.gov/pubmed/26512919

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