Cargando…

Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells

Distant relapse after chemotherapy is an important clinical issue for treating breast cancer patients and results from the development of cancer stem-like cells (CSCs) during chemotherapy. Here we report that blocking epithelial-to-mesenchymal transition (EMT) suppresses paclitaxel-induced CSCs prop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, So-Yeon, Kim, Min-Jin, Park, Sang-A, Kim, Jung-Shin, Min, Kyung-Nan, Kim, Dae-Kee, Lim, Woosung, Nam, Jeong-Seok, Sheen, Yhun Yhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741946/ https://www.ncbi.nlm.nih.gov/pubmed/26462028

Ejemplares similares

TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling
por: Park, Sang-A, et al.
Publicado: (2015)

Targeting the Transforming Growth Factor-β Signaling in Cancer Therapy
por: Sheen, Yhun Yhong, et al.
Publicado: (2013)

Anti-Cancer Effect of 3-(4-dimethylamino phenyl)-N-hydroxy-2-propenamide in MCF-7 Human Breast Cancer
por: Min, Kyung Nan, et al.
Publicado: (2012)

Anti-Cancer Effect of IN-2001 in T47D Human Breast Cancer
por: Joung, Ki Eun, et al.
Publicado: (2012)

Anti-Cancer Effect of IN-2001 in MDA-MB-231 Human Breast Cancer
por: Min, Kyung Nan, et al.
Publicado: (2012)

Radiotherapy-induced oxidative stress and fibrosis in breast cancer are suppressed by vactosertib, a novel, orally bioavailable TGF-β/ALK5 inhibitor
por: Park, Jiyoung, et al.
Publicado: (2022)

Alpha1-Antitrypsin Attenuates Renal Fibrosis by Inhibiting TGF-β1-Induced Epithelial Mesenchymal Transition
por: Cho, Jang-Hee, et al.
Publicado: (2016)

Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-β signaling
por: Kaowinn, Sirichat, et al.
Publicado: (2016)

TGF-β1 Receptor Inhibitor SB525334 Attenuates the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells via the TGF-β1 Signaling Pathway
por: Heo, Jung-Yoon, et al.
Publicado: (2021)

Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition
por: Kyung, Sun Young, et al.
Publicado: (2018)

Apolipoprotein A1 Inhibits TGF-β1–Induced Epithelial-to-Mesenchymal Transition of Alveolar Epithelial Cells
por: Baek, Ae Rin, et al.
Publicado: (2016)

Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes
por: Steinway, Steven Nathaniel, et al.
Publicado: (2015)

DNMTs Are Involved in TGF-β1-Induced Epithelial–Mesenchymal Transitions in Airway Epithelial Cells
por: Park, Joo-Hoo, et al.
Publicado: (2022)

β-Peltoboykinolic Acid from Astilbe rubra Attenuates TGF-β1-Induced Epithelial-to-Mesenchymal Transitions in Lung Alveolar Epithelial Cells
por: Bang, In Jae, et al.
Publicado: (2019)

Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
por: Li, Jingpei, et al.
Publicado: (2020)

Crizotinib attenuates cancer metastasis by inhibiting TGFβ signaling in non-small cell lung cancer cells
por: Park, Soonbum, et al.
Publicado: (2022)

Trichostatin A Inhibits Epithelial Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium
por: Park, Il-Ho, et al.
Publicado: (2016)

CD82 attenuates TGF-β1-mediated epithelial-mesenchymal transition by blocking smad-dependent signaling in ARPE-19 cells
por: Lee, Hyesook, et al.
Publicado: (2022)

Paricalcitol Attenuates 4-Hydroxy-2-Hexenal-Induced Inflammation and Epithelial-Mesenchymal Transition in Human Renal Proximal Tubular Epithelial Cells
por: Kim, Chang Seong, et al.
Publicado: (2013)

β-catenin activates TGF-β-induced epithelial–mesenchymal transition in adenomyosis
por: Yoo, Jung-Yoon, et al.
Publicado: (2020)

Curcumol attenuates epithelial-mesenchymal transition of nasopharyngeal carcinoma cells via TGF-β1
por: Yan, Dazhong, et al.
Publicado: (2018)

Correction: Paricalcitol Attenuates 4-Hydroxy-2-Hexenal-Induced Inflammation and Epithelial-Mesenchymal Transition in Human Renal Proximal Tubular Epithelial Cells
por: Kim, Chang Seong, et al.
Publicado: (2013)

Evaluation of pH-Sensitive Polymeric Micelles Using Citraconic Amide Bonds for the Co-Delivery of Paclitaxel, Etoposide, and Rapamycin
por: Jo, Min Jeong, et al.
Publicado: (2023)

Effects of TGF-β1 Receptor Inhibitor GW788388 on the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells
por: Lho, Yunmee, et al.
Publicado: (2021)

Synergistic Encapsulation of Paclitaxel and Sorafenib by Methoxy Poly(Ethylene Glycol)-b-Poly(Caprolactone) Polymeric Micelles for Ovarian Cancer Therapy
por: Jin, Chae Eun, et al.
Publicado: (2023)

Novel oral transforming growth factor‐β signaling inhibitor EW‐7197 eradicates CML‐initiating cells
por: Naka, Kazuhito, et al.
Publicado: (2016)

Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling
por: Park, Jinah, et al.
Publicado: (2013)

Combinatorial perturbation analysis reveals divergent regulations of mesenchymal genes during epithelial-to-mesenchymal transition
por: Watanabe, Kazuhide, et al.
Publicado: (2019)

Recombinant Human HAPLN1 Mitigates Pulmonary Emphysema by Increasing TGF-β Receptor I and Sirtuins Levels in Human Alveolar Epithelial Cells
por: Piao, Yongwei, et al.
Publicado: (2023)

A Real-World Efficacy of Nab-Paclitaxel Monotherapy in Metastatic Breast Cancer
por: Kim, Jung Sun, et al.
Publicado: (2022)

Development of paclitaxel-loaded liposomal nanocarrier stabilized by triglyceride incorporation
por: Hong, Soon-Seok, et al.
Publicado: (2016)

Effects of Epigallocatechin-3-Gallate on the Expression of TGF-β1, PKC α/βII, and NF-κB in High-Glucose-Stimulated Glomerular Epithelial Cells
por: Park, Sung Jun, et al.
Publicado: (2011)

Cardamonin Suppresses TGF-β1-Induced Epithelial Mesenchymal Transition via Restoring Protein Phosphatase 2A Expression
por: Kim, Eun Ji, et al.
Publicado: (2015)

Dlx-2 and glutaminase upregulate epithelial-mesenchymal transition and glycolytic switch
por: Lee, Su Yeon, et al.
Publicado: (2016)

Lodoxamide Attenuates Hepatic Fibrosis in Mice: Involvement of GPR35
por: Kim, Mi-Jeong, et al.
Publicado: (2020)

Microparticles derived from human erythropoietin mRNA-transfected mesenchymal stem cells inhibit epithelial-to-mesenchymal transition and ameliorate renal interstitial fibrosis
por: Lee, Mirae, et al.
Publicado: (2020)

Atractylodin Suppresses TGF-β-Mediated Epithelial-Mesenchymal Transition in Alveolar Epithelial Cells and Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
por: Chang, Kai-Wei, et al.
Publicado: (2021)

Blue light attenuates TGF-β2-induced epithelial-mesenchymal transition in human lens epithelial cells via autophagy impairment
por: Zhang, Dongyan, et al.
Publicado: (2022)

Oleanolic acid attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells
por: He, Wei-ming, et al.
Publicado: (2018)

miR-29b Regulates TGF-β1-Induced Epithelial–Mesenchymal Transition by Inhibiting Heat Shock Protein 47 Expression in Airway Epithelial Cells
por: Shin, Jae-Min, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_86qk6sfbme3bhne468d3ufsejh