Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma

Crk is the prototypical member of a class of Src homology 2 (SH2) and Src homology 3 (SH3) domain-containing adaptor proteins that positively regulate cell motility via the activation of Rac1 and, in certain tumor types such as GBM, can promote cell invasion and metastasis by mechanisms that are not...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Sushil, Lu, Bin, Dixit, Updesh, Hossain, Sajjad, Liu, Yongzhang, Li, Jing, Hornbeck, Peter, Zheng, Weiming, Sowalsky, Adam G., Kotula, Leszek, Birge, Raymond B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741966/
https://www.ncbi.nlm.nih.gov/pubmed/26473374

Ejemplares similares

Ejemplares similares