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Usp22 deficiency impairs intestinal epithelial lineage specification in vivo
Epigenetic regulatory mechanisms play a central role in controlling gene expression during development, cell differentiation and tumorigenesis. Monoubiquitination of histone H2B is one epigenetic modification which is dynamically regulated by the opposing activities of specific ubiquitin ligases and...
Autores principales: | Kosinsky, Robyn L., Wegwitz, Florian, Hellbach, Nicole, Dobbelstein, Matthias, Mansouri, Ahmed, Vogel, Tanja, Begus-Nahrmann, Yvonne, Johnsen, Steven A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741973/ https://www.ncbi.nlm.nih.gov/pubmed/26431380 |
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