Loss of the epigenetic mark, 5-Hydroxymethylcytosine, correlates with small cell/nevoid subpopulations and assists in microstaging of human melanoma

Melanomas in the vertical growth phase (VGP) not infrequently demonstrate cellular heterogeneity. One commonly encountered subpopulation displays small cell/nevoid morphology. Although its significance remains unknown, such subpopulations may pose diagnostic issues when faced with differentiating su...

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Detalles Bibliográficos
Autores principales: Lee, Jonathan J., Cook, Martin, Mihm, Martin C., Xu, Shuyun, Zhan, Qian, Wang, Thomas J., Murphy, George F., Lian, Christine G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741979/
https://www.ncbi.nlm.nih.gov/pubmed/26462027

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