Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells

The BH3-only protein PUMA (p53-upregulated modulator of apoptosis) is a major regulator of apoptosis. It belongs to the Bcl-2 family of proteins responsible for maintaining mitochondrial outer membrane integrity by controlling the intrinsic (mitochondrial) apoptotic pathway. We describe here a new p...

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Detalles Bibliográficos
Autores principales: Ambroise, Gorbatchev, Portier, Alain, Roders, Nathalie, Arnoult, Damien, Vazquez, Aimé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741992/
https://www.ncbi.nlm.nih.gov/pubmed/26431330

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