Etoposide enhances antitumor efficacy of MDR1-driven oncolytic adenovirus through autoupregulation of the MDR1 promoter activity

Conditionally replicating adenoviruses (CRAds), or oncolytic adenoviruses, such as E1B55K-deleted adenovirus, are attractive anticancer agents. However, the therapeutic efficacy of E1B55K-deleted adenovirus for refractory solid tumors has been limited. Environmental stress conditions may induce nucl...

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Detalles Bibliográficos
Autores principales: Su, Bing-Hua, Shieh, Gia-Shing, Tseng, Yau-Lin, Shiau, Ai-Li, Wu, Chao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742001/
https://www.ncbi.nlm.nih.gov/pubmed/26515462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742001/
https://www.ncbi.nlm.nih.gov/pubmed/26515462

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