Cargando…

The use of personalized biomarkers and liquid biopsies to monitor treatment response and disease recurrence in locally advanced rectal cancer after neoadjuvant chemoradiation

Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is the mainstay treatment for locally advanced rectal cancer. Variable degrees of tumor regression are observed after nCRT and alternative treatment strategies, including close surveillance without immediate surgery, have been investigated to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carpinetti, Paola, Donnard, Elisa, Bettoni, Fabiana, Asprino, Paula, Koyama, Fernanda, Rozanski, Andrei, Sabbaga, Jorge, Habr-Gama, Angelita, Parmigiani, Raphael B., Galante, Pedro A.F., Perez, Rodrigo O., Camargo, Anamaria A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742005/ https://www.ncbi.nlm.nih.gov/pubmed/26451609

Ejemplares similares

The Effects of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer—The Impact in Intratumoral Heterogeneity
por: Bettoni, Fabiana, et al.
Publicado: (2019)

Overexpression of miR-21-5p as a predictive marker for complete tumor regression to neoadjuvant chemoradiotherapy in rectal cancer patients
por: Lopes-Ramos, Camila Miranda, et al.
Publicado: (2014)

Consolidation chemotherapy during neoadjuvant chemoradiation (CRT) for distal rectal cancer leads to sustained decrease in tumor metabolism when compared to standard CRT regimen
por: Habr-Gama, Angelita, et al.
Publicado: (2016)

E2F1 somatic mutation within miRNA target site impairs gene regulation in colorectal cancer
por: Lopes-Ramos, Camila M., et al.
Publicado: (2017)

Mutational analysis of genes coding for cell surface proteins in colorectal cancer cell lines reveal novel altered pathways, druggable mutations and mutated epitopes for targeted therapy
por: Donnard, Elisa, et al.
Publicado: (2014)

Suspected Germline TP53 Variants and Clonal Hematopoiesis of Indeterminate Potential: Lessons Learned From a Molecular Tumor Board
por: Xavier, Camila B, et al.
Publicado: (2023)

Clinical outcome of neoadjuvant chemoradiation in rectal cancer treatment
por: Suwanthanma, Weerapat, et al.
Publicado: (2021)

Neoadjuvant chemoradiation therapy and pathological complete response in rectal cancer
por: Ferrari, Linda, et al.
Publicado: (2015)

Watch and Wait Approach for Rectal Cancer
por: Cerdan-Santacruz, Carlos, et al.
Publicado: (2023)

Neoadjuvant chemoradiation for rectal cancer in patients aged 75 years or older
por: Lombardi, Raffaele, et al.
Publicado: (2009)

Aspirin as a neoadjuvant agent during preoperative chemoradiation for rectal cancer
por: Restivo, Angelo, et al.
Publicado: (2015)

Predictive and Prognostic Molecular Biomarkers for Response to Neoadjuvant Chemoradiation in Rectal Cancer
por: Dayde, Delphine, et al.
Publicado: (2017)

Circulating Tumor DNA Detection in the Management of Anti-EGFR Therapy for Advanced Colorectal Cancer
por: Knebel, Franciele H., et al.
Publicado: (2019)

Neoadjuvant Chemoradiation Combined with Regional Hyperthermia in Locally Advanced or Recurrent Rectal Cancer
por: Ott, Oliver J., et al.
Publicado: (2021)

Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer
por: Dayde, Delphine, et al.
Publicado: (2021)

Optimized tools and timing of response reassessment after neoadjuvant chemoradiation in rectal cancer
por: Chen, Junbing, et al.
Publicado: (2022)

Preoperative MRI accuracy after neoadjuvant chemoradiation for locally advanced rectal cancer
por: Popiţa, Anca-Raluca, et al.
Publicado: (2023)

A multi-centre randomized controlled trial investigating Consolidation Chemotherapy with and without oxaliplatin in distal rectal cancer and Watch & Wait
por: Habr-Gama, Angelita, et al.
Publicado: (2023)

Optimal timing of surgery after neoadjuvant chemoradiation therapy in locally advanced rectal cancer
por: Jeong, Duck Hyoun, et al.
Publicado: (2013)

Association of tumor differentiation and prognosis in patients with rectal cancer undergoing neoadjuvant chemoradiation therapy
por: Huang, Qunsheng, et al.
Publicado: (2019)

Neoadjuvant chemoradiation alters biomarkers of anticancer immunotherapy responses in locally advanced rectal cancer
por: Seo, Incheol, et al.
Publicado: (2021)

Evaluation and Predictive Factors of Complete Response in Rectal Cancer after Neoadjuvant Chemoradiation Therapy
por: Kokaine, Linda, et al.
Publicado: (2021)

Comparing outcomes following total neoadjuvant therapy and following neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer
por: Zhu, Shaoyu, et al.
Publicado: (2019)

Impact of the distal resection margin on local recurrence after neoadjuvant chemoradiation and rectal excision for locally advanced rectal cancer
por: Song, Seung Ho, et al.
Publicado: (2021)

Neoadjuvant chemotherapy prior to preoperative chemoradiation or radiation in rectal cancer: should we be more cautious?
por: Glynne-Jones, R, et al.
Publicado: (2006)

Tumor regression in rectal cancer after intensified neoadjuvant chemoradiation: a morphometric and clinicopathological study
por: Prall, Friedrich, et al.
Publicado: (2015)

Obesity as an independent predictive factor for pathologic complete response after neoadjuvant chemoradiation in rectal cancer
por: Lee, Soo Young, et al.
Publicado: (2019)

The Impact of Chronic Kidney Disease in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation
por: Dudani, Shaan, et al.
Publicado: (2021)

Predicting outcomes for locally advanced rectal cancer treated with neoadjuvant chemoradiation with CT-based radiomics
por: Wang, Fuqiang, et al.
Publicado: (2022)

TSC2 rare germline variants in non-tuberous sclerosis patients with neuroendocrine neoplasias
por: Asprino, Paula Fontes, et al.
Publicado: (2017)

What does absence of lymph node in resected specimen mean after neoadjuvant chemoradiation for rectal cancer
por: Lee, Won-Suk, et al.
Publicado: (2013)

Neoadjuvant chemoradiation for locally advanced rectal cancer: a systematic review of the literature with network meta-analysis
por: Chen, Min, et al.
Publicado: (2019)

The changes of tumour vascular endothelial growth factor expression after neoadjuvant chemoradiation in patients with rectal adenocarcinoma
por: Buka, David, et al.
Publicado: (2017)

3.0 T MRI IVIM-DWI for predicting the efficacy of neoadjuvant chemoradiation for locally advanced rectal cancer
por: Hu, Hongbo, et al.
Publicado: (2020)

Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies
por: Jo, Peter, et al.
Publicado: (2016)

Neoadjuvant systemic fluorouracil and mitomycin C prior to synchronous chemoradiation is an effective strategy in locally advanced rectal cancer
por: Chau, I, et al.
Publicado: (2003)

Short–term effects of neoadjuvant chemoradiation therapy on anorectal function in rectal cancer patients: a pilot study
por: Kye, Bong-Hyeon, et al.
Publicado: (2013)

Extramural depth of rectal cancer tumor invasion at thin-section MRI: predicting treatment response to neoadjuvant chemoradiation
por: Tong, Tong, et al.
Publicado: (2015)

Focal adhesion kinase: predictor of tumour response and risk factor for recurrence after neoadjuvant chemoradiation in rectal cancer
por: Gómez del Pulgar, Teresa, et al.
Publicado: (2016)

Does Extending the Waiting Time of Low-Rectal Cancer Surgery after Neoadjuvant Chemoradiation Increase the Perioperative Complications?
por: Timudom, Kittinut, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bg59opudiorf8pl4binupu0bba