Adenocarcinoma arising from chronic perianal crohn's disease: a case report

Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas. A 36-year-old male, diagnosed with Crohn's disease at the age of 24, developed adenocarcinoma in an anorectal fistula that ha...

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Autores principales: Massit, Hanane, Edderai, Meryem, Saouab, Rachida, Seddik, Hassan, El Fenni, Jamal, Benkirane, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742036/
https://www.ncbi.nlm.nih.gov/pubmed/26889321
http://dx.doi.org/10.11604/pamj.2015.22.140.7875
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author Massit, Hanane
Edderai, Meryem
Saouab, Rachida
Seddik, Hassan
El Fenni, Jamal
Benkirane, Ahmed
author_facet Massit, Hanane
Edderai, Meryem
Saouab, Rachida
Seddik, Hassan
El Fenni, Jamal
Benkirane, Ahmed
author_sort Massit, Hanane
collection PubMed
description Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas. A 36-year-old male, diagnosed with Crohn's disease at the age of 24, developed adenocarcinoma in an anorectal fistula that had existed for years. He was treated with adjuvant chemoradiotherapy but died. A high index of suspicion and regular surveillance is recommended in chronic anorectal fistulas in Crohn's disease. The shorter duration of Crohn's fistulas prior to malignant degeneration necessitates an aggressive approach to rule out cancer.
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spelling pubmed-47420362016-02-17 Adenocarcinoma arising from chronic perianal crohn's disease: a case report Massit, Hanane Edderai, Meryem Saouab, Rachida Seddik, Hassan El Fenni, Jamal Benkirane, Ahmed Pan Afr Med J Case Report Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. We report a case of Crohn's disease with recurrent perineal fistulas. A 36-year-old male, diagnosed with Crohn's disease at the age of 24, developed adenocarcinoma in an anorectal fistula that had existed for years. He was treated with adjuvant chemoradiotherapy but died. A high index of suspicion and regular surveillance is recommended in chronic anorectal fistulas in Crohn's disease. The shorter duration of Crohn's fistulas prior to malignant degeneration necessitates an aggressive approach to rule out cancer. The African Field Epidemiology Network 2015-10-14 /pmc/articles/PMC4742036/ /pubmed/26889321 http://dx.doi.org/10.11604/pamj.2015.22.140.7875 Text en © Hanane Massit et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Massit, Hanane
Edderai, Meryem
Saouab, Rachida
Seddik, Hassan
El Fenni, Jamal
Benkirane, Ahmed
Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title_full Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title_fullStr Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title_full_unstemmed Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title_short Adenocarcinoma arising from chronic perianal crohn's disease: a case report
title_sort adenocarcinoma arising from chronic perianal crohn's disease: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742036/
https://www.ncbi.nlm.nih.gov/pubmed/26889321
http://dx.doi.org/10.11604/pamj.2015.22.140.7875
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