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Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant
Flagellin has been tested as a protein-based vaccine adjuvant, with the majority of studies focused on antibody responses. Here, we evaluated the adjuvant activity of flagellin for both cellular and humoral immune responses in BALB/c mice in the setting of gene-based immunization, and have made seve...
Autores principales: | Rady, Hamada F., Dai, Guixiang, Huang, Weitao, Shellito, Judd E., Ramsay, Alistair J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742079/ https://www.ncbi.nlm.nih.gov/pubmed/26844553 http://dx.doi.org/10.1371/journal.pone.0148701 |
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