Chromosome transplantation as a novel approach for correcting complex genomic disorders

Genomic disorders resulting from large rearrangements of the genome remain an important unsolved issue in gene therapy. Chromosome transplantation, defined as the perfect replacement of an endogenous chromosome with a homologous one, has the potential of curing this kind of disorders. Here we report...

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Detalles Bibliográficos
Autores principales: Paulis, Marianna, Castelli, Alessandra, Susani, Lucia, Lizier, Michela, Lagutina, Irina, Focarelli, Maria Luisa, Recordati, Camilla, Uva, Paolo, Faggioli, Francesca, Neri, Tui, Scanziani, Eugenio, Galli, Cesare, Lucchini, Franco, Villa, Anna, Vezzoni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742100/
https://www.ncbi.nlm.nih.gov/pubmed/26485770

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