Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma

Despite advances in multimodal treatment, neuroblastoma (NB) is often fatal for children with high-risk disease and many survivors need to cope with long-term side effects from high-dose chemotherapy and radiation. To identify new therapeutic targets, we performed an siRNA screen of the druggable ge...

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Detalles Bibliográficos
Autores principales: Bogen, Dominik, Wei, Jun S., Azorsa, David O., Ormanoglu, Pinar, Buehler, Eugen, Guha, Rajarshi, Keller, Jonathan M., Griner, Lesley A. Mathews, Ferrer, Marc, Song, Young K., Liao, Hongling, Mendoza, Arnulfo, Gryder, Berkley E., Sindri, Sivasish, He, Jianbin, Wen, Xinyu, Zhang, Shile, Shern, John F., Yohe, Marielle E., Taschner-Mandl, Sabine, Shohet, Jason M., Thomas, Craig J., Martin, Scott E., Ambros, Peter F., Khan, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742102/
https://www.ncbi.nlm.nih.gov/pubmed/26497213

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