RAGE mediated intracellular Aβ uptake contributes to the breakdown of tight junction in retinal pigment epithelium

Intracellular amyloid beta (Aβ) has been implicated in neuronal cell death in Alzheimer's disease (AD). Intracellular Aβ also contributes to tight junction breakdown of retinal pigment epithelium (RPE) in age-related macular degeneration (AMD). Although Aβ is predominantly secreted from neurona...

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Detalles Bibliográficos
Autores principales: Park, Sung Wook, Kim, Jin Hyoung, Park, Sang Min, Moon, Minho, Lee, Kihwang, Park, Kyu Hyung, Park, Woo Jin, Kim, Jeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742103/
https://www.ncbi.nlm.nih.gov/pubmed/26431165

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