The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

Overexpression of heat shock protein 90 (HSP90) is associated with increased tumor cell survival and radioresistance. In this study we explored the efficacy of the novel HSP90 inhibitor AT13387 and examined its radiosensitizing effects in combination with gamma-radiation in 2D and 3D structures as w...

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Detalles Bibliográficos
Autores principales: Spiegelberg, Diana, Dascalu, Adrian, Mortensen, Anja C., Abramenkovs, Andris, Kuku, Gamze, Nestor, Marika, Stenerlöw, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742132/
https://www.ncbi.nlm.nih.gov/pubmed/26452257

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