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Pharmacologic regulation of AMPK in breast cancer affects cytoskeletal properties involved with microtentacle formation and re-attachment
The presence of tumor cells in the circulation is associated with a higher risk of metastasis in patients with breast cancer. Circulating breast tumor cells use tubulin-based structures known as microtentacles (McTNs) to re-attach to endothelial cells and arrest in distant organs. McTN formation is...
Autores principales: | Chakrabarti, Kristi R., Whipple, Rebecca A., Boggs, Amanda E., Hessler, Lindsay K., Bhandary, Lekhana, Vitolo, Michele I., Thompson, Keyata, Martin, Stuart S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742178/ https://www.ncbi.nlm.nih.gov/pubmed/26431377 |
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