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Quinacrine promotes autophagic cell death and chemosensitivity in ovarian cancer and attenuates tumor growth

A promising new strategy for cancer therapy is to target the autophagic pathway. In the current study, we demonstrate that the antimalarial drug Quinacrine (QC) reduces cell viability and promotes chemotherapy-induced cell death in an autophagy-dependent manner more extensively in chemoresistant cel...

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Detalles Bibliográficos
Autores principales: Khurana, Ashwani, Roy, Debarshi, Kalogera, Eleftheria, Mondal, Susmita, Wen, Xuyang, He, Xiaoping, Dowdy, Sean, Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742182/
https://www.ncbi.nlm.nih.gov/pubmed/26497553

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