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Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories

Although many human diseases have a genetic component involving many loci, the majority of studies are statistically underpowered to isolate the many contributing variants, raising the question of the existence of alternate processes to identify disease mutations. To address this question, we collec...

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Detalles Bibliográficos
Autores principales: Guturu, Harendra, Chinchali, Sandeep, Clarke, Shoa L., Bejerano, Gill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742230/
https://www.ncbi.nlm.nih.gov/pubmed/26845687
http://dx.doi.org/10.1371/journal.pcbi.1004711