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Erosion of Conserved Binding Sites in Personal Genomes Points to Medical Histories
Although many human diseases have a genetic component involving many loci, the majority of studies are statistically underpowered to isolate the many contributing variants, raising the question of the existence of alternate processes to identify disease mutations. To address this question, we collec...
Autores principales: | Guturu, Harendra, Chinchali, Sandeep, Clarke, Shoa L., Bejerano, Gill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742230/ https://www.ncbi.nlm.nih.gov/pubmed/26845687 http://dx.doi.org/10.1371/journal.pcbi.1004711 |
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