Cargando…

Novel Roles for K(v)7 Channels in Shaping Histamine-Induced Contractions and Bradykinin-Dependent Relaxations in Pig Coronary Arteries

Voltage-gated K(v)7 channels are inhibited by agonists of G(q)-protein-coupled receptors, such as histamine. Recent works have provided evidence that inhibition of vascular K(v)7 channels may trigger vessel contractions. In this study, we investigated how K(v)7 activity modulates the histamine-induc...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xingjuan, Li, Wennan, Hiett, S. Christopher, Obukhov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742238/
https://www.ncbi.nlm.nih.gov/pubmed/26844882
http://dx.doi.org/10.1371/journal.pone.0148569