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BS69/ZMYND11 C-Terminal Domains Bind and Inhibit EBNA2

Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) plays an important role in driving immortalization of EBV-infected B cells through regulating the expression of many viral and cellular genes. We report a structural study of the tumor suppressor BS69/ZMYND11 C-terminal region, comprised of tandem c...

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Detalles Bibliográficos
Autores principales: Harter, Matthew R., Liu, Cheng-Der, Shen, Chih-Lung, Gonzalez-Hurtado, Elsie, Zhang, Zhi-Min, Xu, Muyu, Martinez, Ernest, Peng, Chih-Wen, Song, Jikui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742278/
https://www.ncbi.nlm.nih.gov/pubmed/26845565
http://dx.doi.org/10.1371/journal.ppat.1005414