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Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency prof...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korea Genome Organization
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742326/ https://www.ncbi.nlm.nih.gov/pubmed/26865847 http://dx.doi.org/10.5808/GI.2015.13.4.152 |
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author | Lent, Heather Lee, Kyung-Eun Park, Hyun-Seok |
author_facet | Lent, Heather Lee, Kyung-Eun Park, Hyun-Seok |
author_sort | Lent, Heather |
collection | PubMed |
description | Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function. |
format | Online Article Text |
id | pubmed-4742326 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Korea Genome Organization |
record_format | MEDLINE/PubMed |
spelling | pubmed-47423262016-02-10 Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective Lent, Heather Lee, Kyung-Eun Park, Hyun-Seok Genomics Inform Application Note Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function. Korea Genome Organization 2015-12 2015-12-31 /pmc/articles/PMC4742326/ /pubmed/26865847 http://dx.doi.org/10.5808/GI.2015.13.4.152 Text en Copyright © 2015 by the Korea Genome Organization http://creativecommons.org/licenses/by-nc/4.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/). |
spellingShingle | Application Note Lent, Heather Lee, Kyung-Eun Park, Hyun-Seok Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title_full | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title_fullStr | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title_full_unstemmed | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title_short | Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective |
title_sort | building the frequency profile of the core promoter element patterns in the three chromhmm promoter states at 200bp intervals: a statistical perspective |
topic | Application Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742326/ https://www.ncbi.nlm.nih.gov/pubmed/26865847 http://dx.doi.org/10.5808/GI.2015.13.4.152 |
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