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Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective

Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency prof...

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Detalles Bibliográficos
Autores principales: Lent, Heather, Lee, Kyung-Eun, Park, Hyun-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742326/
https://www.ncbi.nlm.nih.gov/pubmed/26865847
http://dx.doi.org/10.5808/GI.2015.13.4.152
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author Lent, Heather
Lee, Kyung-Eun
Park, Hyun-Seok
author_facet Lent, Heather
Lee, Kyung-Eun
Park, Hyun-Seok
author_sort Lent, Heather
collection PubMed
description Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function.
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spelling pubmed-47423262016-02-10 Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective Lent, Heather Lee, Kyung-Eun Park, Hyun-Seok Genomics Inform Application Note Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function. Korea Genome Organization 2015-12 2015-12-31 /pmc/articles/PMC4742326/ /pubmed/26865847 http://dx.doi.org/10.5808/GI.2015.13.4.152 Text en Copyright © 2015 by the Korea Genome Organization http://creativecommons.org/licenses/by-nc/4.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Application Note
Lent, Heather
Lee, Kyung-Eun
Park, Hyun-Seok
Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title_full Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title_fullStr Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title_full_unstemmed Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title_short Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
title_sort building the frequency profile of the core promoter element patterns in the three chromhmm promoter states at 200bp intervals: a statistical perspective
topic Application Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742326/
https://www.ncbi.nlm.nih.gov/pubmed/26865847
http://dx.doi.org/10.5808/GI.2015.13.4.152
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