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L-selectin Is Essential for Delivery of Activated CD8(+) T Cells to Virus-Infected Organs for Protective Immunity

Cytotoxic CD8(+) T lymphocytes play a critical role in the host response to infection by viruses. The ability to secrete cytotoxic chemicals and cytokines is considered pivotal for eliminating virus. Of equal importance is how effector CD8(+) T cells home to virus-infected tissues. L-selectin has no...

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Detalles Bibliográficos
Autores principales: Mohammed, Rebar N., Watson, H. Angharad, Vigar, Miriam, Ohme, Julia, Thomson, Amanda, Humphreys, Ian R., Ager, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742564/
https://www.ncbi.nlm.nih.gov/pubmed/26804910
http://dx.doi.org/10.1016/j.celrep.2015.12.090