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Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes
Extracellular fibrinogen-binding protein (Efb) from Staphylococcus aureus inhibits platelet activation, although its mechanism of action has not been established. In this study, we discovered that the N-terminal region of Efb (Efb-N) promotes platelet binding of fibrinogen and that Efb-N binding to...
Autores principales: | Posner, Mareike G., Upadhyay, Abhishek, Abubaker, Aisha Alsheikh, Fortunato, Tiago M., Vara, Dina, Canobbio, Ilaria, Bagby, Stefan, Pula, Giordano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742742/ https://www.ncbi.nlm.nih.gov/pubmed/26627825 http://dx.doi.org/10.1074/jbc.M115.678359 |
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