Amino acid changes in PB2 and HA affect the growth of a recombinant influenza virus expressing a fluorescent reporter protein

Influenza viruses that express reporter proteins are useful tools, but are often attenuated. Recently, we found that an influenza virus encoding the Venus fluorescent protein acquired two mutations in its PB2 and HA proteins upon mouse adaptation. Here, we demonstrate that the enhanced viral replica...

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Detalles Bibliográficos
Autores principales: Katsura, Hiroaki, Fukuyama, Satoshi, Watanabe, Shinji, Ozawa, Makoto, Neumann, Gabriele, Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742795/
https://www.ncbi.nlm.nih.gov/pubmed/26847414
http://dx.doi.org/10.1038/srep19933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742795/
https://www.ncbi.nlm.nih.gov/pubmed/26847414
http://dx.doi.org/10.1038/srep19933

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