Cargando…

Load-dependent modulation of non-muscle myosin-2A function by tropomyosin 4.2

Tropomyosin isoforms play an important role in the organisation of cytoplasmic actomyosin complexes in regard to function and cellular localisation. In particular, Tpm4.2 is upregulated in rapidly migrating cells and responsible for the specific recruitment of the cytoplasmic class-2 myosin NM-2A to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hundt, Nikolas, Steffen, Walter, Pathan-Chhatbar, Salma, Taft, Manuel H., Manstein, Dietmar J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742800/ https://www.ncbi.nlm.nih.gov/pubmed/26847712 http://dx.doi.org/10.1038/srep20554

Ejemplares similares

Three mammalian tropomyosin isoforms have different regulatory effects on nonmuscle myosin-2B and filamentous β-actin in vitro
por: Pathan-Chhatbar, Salma, et al.
Publicado: (2018)

Distinct actin–tropomyosin cofilament populations drive the functional diversification of cytoskeletal myosin motor complexes
por: Reindl, Theresia, et al.
Publicado: (2022)

Actin–tropomyosin distribution in non-muscle cells
por: Manstein, Dietmar J., et al.
Publicado: (2019)

Nonmuscle myosin-2: mix and match
por: Heissler, Sarah M., et al.
Publicado: (2012)

Myosin and tropomyosin–troponin complementarily regulate thermal activation of muscles
por: Ishii, Shuya, et al.
Publicado: (2023)

Regulation of Nonmuscle Myosin II by Tropomyosin
por: Barua, Bipasha, et al.
Publicado: (2014)

Small molecule-mediated refolding and activation of myosin motor function
por: Radke, Michael B, et al.
Publicado: (2014)

Mechanochemical properties of human myosin-1C are modulated by isoform-specific differences in the N-terminal extension
por: Giese, Sven, et al.
Publicado: (2020)

cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
por: Zou, Lihui, et al.
Publicado: (2018)

Assessment of the Contribution of a Thermodynamic and Mechanical Destabilization of Myosin-Binding Protein C Domain C2 to the Pathomechanism of Hypertrophic Cardiomyopathy-Causing Double Mutation MYBPC3(Δ25bp/D389V)
por: Schwäbe, Frederic V., et al.
Publicado: (2021)

Global Fit Analysis of Myosin-5b Motility Reveals Thermodynamics of Mg(2+)-Sensitive Acto-Myosin-ADP States
por: Chizhov, Igor, et al.
Publicado: (2013)

Distinct Functional Interactions between Actin Isoforms and Nonsarcomeric Myosins
por: Müller, Mirco, et al.
Publicado: (2013)

Comparative Kinetic and Functional Characterization of the Motor Domains of Human Nonmuscle Myosin-2C Isoforms
por: Heissler, Sarah M., et al.
Publicado: (2011)

Developmental Profiling of Tropomyosin Expression in Mouse Brain Reveals Tpm4.2 as the Major Post-synaptic Tropomyosin in the Mature Brain
por: Suchowerska, Alexandra K., et al.
Publicado: (2017)

Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation
por: Doran, Matthew H., et al.
Publicado: (2022)

Studies on cardiac myofibrillogenesis with antibodies to titin, actin, tropomyosin, and myosin
Publicado: (1988)

Myosin and Tropomyosin Stabilize the Conformation of Formin-nucleated Actin Filaments
por: Ujfalusi, Zoltán, et al.
Publicado: (2012)

Functional characterization of the human myosin-7a motor domain
por: Heissler, Sarah M., et al.
Publicado: (2011)

Tropomyosin Isoforms Specify Functionally Distinct Actin Filament Populations In Vitro
por: Gateva, Gergana, et al.
Publicado: (2017)

Stabilization of the Central Part of Tropomyosin Molecule Alters the Ca2+-sensitivity of Actin-Myosin Interaction
por: Shchepkin, D.V., et al.
Publicado: (2013)

Structural relationships of actin, myosin, and tropomyosin revealed by cryo-electron microscopy
Publicado: (1987)

Tropomyosin isoforms bias actin track selection by vertebrate myosin Va
por: Sckolnick, Maria, et al.
Publicado: (2016)

Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C
por: Chinthalapudi, Krishna, et al.
Publicado: (2017)

Myosin II governs intracellular pressure and traction by distinct tropomyosin-dependent mechanisms
por: Sao, Kimheak, et al.
Publicado: (2019)

Tropomyosin and Myosin-II Cellular Levels Promote Actomyosin Ring Assembly in Fission Yeast
por: Stark, Benjamin C., et al.
Publicado: (2010)

Fission yeast tropomyosin specifies directed transport of myosin-V along actin cables
por: Clayton, Joseph E., et al.
Publicado: (2014)

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity
por: Chinthalapudi, Krishna, et al.
Publicado: (2011)

Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast
por: Huckaba, Thomas M., et al.
Publicado: (2006)

Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin
por: Doran, Matthew H., et al.
Publicado: (2023)

The Conserved Lysine-265 Allosterically Modulates Nucleotide- and Actin-binding Site Coupling in Myosin-2
por: Behrens, Vincent A., et al.
Publicado: (2017)

Sythesis of tropomyosin in cultures of differentiating muscle cells
Publicado: (1978)

Kinetic properties and small-molecule inhibition of human myosin-6
por: Heissler, Sarah M., et al.
Publicado: (2012)

Localization of myosin, actin, and tropomyosin in rat intestinal epithelium: immunohistochemical studies at the light and electron microscope levels
Publicado: (1980)

A single-headed fission yeast myosin V transports actin in a tropomyosin-dependent manner
por: Tang, Qing, et al.
Publicado: (2016)

Assembly of different isoforms of actin and tropomyosin into the skeletal tropomyosin-enriched microfilaments during differentiation of muscle cells in vitro
Publicado: (1986)

Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells
Publicado: (1975)

Myosin II Filament Dynamics in Actin Networks Revealed with Interferometric Scattering Microscopy
por: Mosby, Lewis S., et al.
Publicado: (2020)

Cdc42 and formin activity control non-muscle myosin dynamics during Drosophila heart morphogenesis
por: Vogler, Georg, et al.
Publicado: (2014)

Caldesmon controls stress fiber force-balance through dynamic cross-linking of myosin II and actin-tropomyosin filaments
por: Kokate, Shrikant B., et al.
Publicado: (2022)

Alterations in flight muscle ultrastructure and function in Drosophila tropomyosin mutants
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_6pbs5lejpqgub67q1t9clllffo