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Novel Method for Neuronal Nanosurgical Connection

Neuronal injury may cause an irreversible damage to cellular, organ and organism function. While preventing neural injury is ideal, it is not always possible. There are multiple etiologies for neuronal injury including trauma, infection, inflammation, immune mediated disorders, toxins and hereditary...

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Detalles Bibliográficos
Autores principales: Katchinskiy, Nir, Goez, Helly R., Dutta, Indrani, Godbout, Roseline, Elezzabi, Abdulhakem Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742801/
https://www.ncbi.nlm.nih.gov/pubmed/26846892
http://dx.doi.org/10.1038/srep20529
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author Katchinskiy, Nir
Goez, Helly R.
Dutta, Indrani
Godbout, Roseline
Elezzabi, Abdulhakem Y.
author_facet Katchinskiy, Nir
Goez, Helly R.
Dutta, Indrani
Godbout, Roseline
Elezzabi, Abdulhakem Y.
author_sort Katchinskiy, Nir
collection PubMed
description Neuronal injury may cause an irreversible damage to cellular, organ and organism function. While preventing neural injury is ideal, it is not always possible. There are multiple etiologies for neuronal injury including trauma, infection, inflammation, immune mediated disorders, toxins and hereditary conditions. We describe a novel laser application, utilizing femtosecond laser pulses, in order to connect neuronal axon to neuronal soma. We were able to maintain cellular viability, and demonstrate that this technique is universal as it is applicable to multiple cell types and media.
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spelling pubmed-47428012016-02-09 Novel Method for Neuronal Nanosurgical Connection Katchinskiy, Nir Goez, Helly R. Dutta, Indrani Godbout, Roseline Elezzabi, Abdulhakem Y. Sci Rep Article Neuronal injury may cause an irreversible damage to cellular, organ and organism function. While preventing neural injury is ideal, it is not always possible. There are multiple etiologies for neuronal injury including trauma, infection, inflammation, immune mediated disorders, toxins and hereditary conditions. We describe a novel laser application, utilizing femtosecond laser pulses, in order to connect neuronal axon to neuronal soma. We were able to maintain cellular viability, and demonstrate that this technique is universal as it is applicable to multiple cell types and media. Nature Publishing Group 2016-02-05 /pmc/articles/PMC4742801/ /pubmed/26846892 http://dx.doi.org/10.1038/srep20529 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Katchinskiy, Nir
Goez, Helly R.
Dutta, Indrani
Godbout, Roseline
Elezzabi, Abdulhakem Y.
Novel Method for Neuronal Nanosurgical Connection
title Novel Method for Neuronal Nanosurgical Connection
title_full Novel Method for Neuronal Nanosurgical Connection
title_fullStr Novel Method for Neuronal Nanosurgical Connection
title_full_unstemmed Novel Method for Neuronal Nanosurgical Connection
title_short Novel Method for Neuronal Nanosurgical Connection
title_sort novel method for neuronal nanosurgical connection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742801/
https://www.ncbi.nlm.nih.gov/pubmed/26846892
http://dx.doi.org/10.1038/srep20529
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