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KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway
Targeting cancer stem cells (CSCs) in colorectal cancer (CRC) remains a difficult problem, as the regulation of CSCs in CRC is poorly understood. Here we demonstrated that KCTD12, potassium channel tetramerization domain containing 12, is down-regulated in the CSC-like cells of CRC. The silencing of...
Autores principales: | Li, Liping, Duan, Tingmei, Wang, Xin, Zhang, Ru-Hua, Zhang, Meifang, Wang, Suihai, Wang, Fen, Wu, Yuanzhong, Huang, Haojie, Kang, Tiebang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742820/ https://www.ncbi.nlm.nih.gov/pubmed/26847701 http://dx.doi.org/10.1038/srep20460 |
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