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Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Sustained epidermal Wnt/β-catenin signalling expands the stem cell compartment and induces ectopic hair follicles (EFs). This is accompanied by extensive fibroblast proliferation and extracellular matrix (ECM) remodelling in the underlying dermis. Here we show that epidermal Hedgehog (Hh) and Transf...
Autores principales: | Lichtenberger, Beate M., Mastrogiannaki, Maria, Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742837/ https://www.ncbi.nlm.nih.gov/pubmed/26837596 http://dx.doi.org/10.1038/ncomms10537 |
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