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Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment
Rapidly growing tumours in vivo often outgrow their surrounding available blood supply, subjecting themselves to a severely hypoxic microenvironment. Understanding how tumour cells adapt themselves to survive hypoxia may help to develop new treatments of the tumours. Given the limited blood perfusio...
Autores principales: | Dong, Hangming, Zou, Mengchen, Bhatia, Ayesha, Jayaprakash, Priyamvada, Hofman, Florence, Ying, Qilong, Chen, Mei, Woodley, David T., Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742873/ https://www.ncbi.nlm.nih.gov/pubmed/26846992 http://dx.doi.org/10.1038/srep20605 |
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