Cargando…
Viral-mediated fusion of mesenchymal stem cells with cells of the infarcted heart hinders healing via decreased vascularization and immune modulation
Cell fusion can occur between mesenchymal stem cells (MSCs) transplanted to improve cardiac function and cells of the recipient. The therapeutic benefit or detriment of resultant cell hybrids is unknown. Here we augment fusion of transplanted MSCs with recipient cardiac cell types via viral fusogens...
Autores principales: | Freeman, Brian T., Ogle, Brenda M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742880/ https://www.ncbi.nlm.nih.gov/pubmed/26846200 http://dx.doi.org/10.1038/srep20283 |
Ejemplares similares
-
Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming
por: Kouris, Nicholas A., et al.
Publicado: (2012) -
Single-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion
por: Freeman, Brian T., et al.
Publicado: (2016) -
Single-Cell RNA-Seq of Bone Marrow-Derived Mesenchymal Stem Cells Reveals Unique Profiles of Lineage Priming
por: Freeman, Brian T., et al.
Publicado: (2015) -
Crippled clock hinders healing
por: Maxmen, Amy
Publicado: (2009) -
Cancer Cell Fusion: Mechanisms Slowly Unravel
por: Noubissi, Felicite K., et al.
Publicado: (2016)