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NuSAP governs chromosome oscillation by facilitating the Kid-generated polar ejection force

In vertebrate cells, chromosomes oscillate to align precisely during metaphase. NuSAP, a microtubule-associated protein, plays a critical role in stabilizing spindle microtubules. In this study, we utilize 3D time-lapse live-cell imaging to monitor the role of NuSAP in chromosome oscillation and ide...

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Detalles Bibliográficos
Autores principales: Li, Chenyu, Xue, Chenyi, Yang, Qiaoyun, Low, Boon Chuan, Liou, Yih-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742958/
https://www.ncbi.nlm.nih.gov/pubmed/26839278
http://dx.doi.org/10.1038/ncomms10597