Intracellular mGluR5 plays a critical role in neuropathic pain

Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here we show that in spinal dorsal horn neurons &g...

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Detalles Bibliográficos
Autores principales: Vincent, Kathleen, Cornea, Virginia M., Jong, Yuh-Jiin I., Laferrière, André, Kumar, Naresh, Mickeviciute, Aiste, Fung, Jollee S. T., Bandegi, Pouya, Ribeiro-da-Silva, Alfredo, O'Malley, Karen L., Coderre, Terence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742982/
https://www.ncbi.nlm.nih.gov/pubmed/26837579
http://dx.doi.org/10.1038/ncomms10604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742982/
https://www.ncbi.nlm.nih.gov/pubmed/26837579
http://dx.doi.org/10.1038/ncomms10604

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