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Intracellular mGluR5 plays a critical role in neuropathic pain
Spinal mGluR5 is a key mediator of neuroplasticity underlying persistent pain. Although brain mGluR5 is localized on cell surface and intracellular membranes, neither the presence nor physiological role of spinal intracellular mGluR5 is established. Here we show that in spinal dorsal horn neurons &g...
Autores principales: | Vincent, Kathleen, Cornea, Virginia M., Jong, Yuh-Jiin I., Laferrière, André, Kumar, Naresh, Mickeviciute, Aiste, Fung, Jollee S. T., Bandegi, Pouya, Ribeiro-da-Silva, Alfredo, O'Malley, Karen L., Coderre, Terence J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742982/ https://www.ncbi.nlm.nih.gov/pubmed/26837579 http://dx.doi.org/10.1038/ncomms10604 |
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