Structure of the poly-C9 component of the complement membrane attack complex

The membrane attack complex (MAC)/perforin-like protein complement component 9 (C9) is the major component of the MAC, a multi-protein complex that forms pores in the membrane of target pathogens. In contrast to homologous proteins such as perforin and the cholesterol-dependent cytolysins (CDCs), al...

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Detalles Bibliográficos
Autores principales: Dudkina, Natalya V., Spicer, Bradley A., Reboul, Cyril F., Conroy, Paul J., Lukoyanova, Natalya, Elmlund, Hans, Law, Ruby H. P., Ekkel, Susan M., Kondos, Stephanie C., Goode, Robert J. A., Ramm, Georg, Whisstock, James C., Saibil, Helen R., Dunstone, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742998/
https://www.ncbi.nlm.nih.gov/pubmed/26841934
http://dx.doi.org/10.1038/ncomms10588

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