Feeding the germline

Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence...

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Detalles Bibliográficos
Autores principales: Shi, Cheng, Murphy, Coleen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743054/
https://www.ncbi.nlm.nih.gov/pubmed/26833726
http://dx.doi.org/10.1101/gad.276980.115
Descripción
Sumario:Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies.

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