Feeding the germline

Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence...

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Detalles Bibliográficos
Autores principales: Shi, Cheng, Murphy, Coleen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Outlook
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743054/
https://www.ncbi.nlm.nih.gov/pubmed/26833726
http://dx.doi.org/10.1101/gad.276980.115
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author Shi, Cheng
Murphy, Coleen T.
author_facet Shi, Cheng
Murphy, Coleen T.
author_sort Shi, Cheng
collection PubMed
description Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies.
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spelling pubmed-47430542016-08-01 Feeding the germline Shi, Cheng Murphy, Coleen T. Genes Dev Outlook Nucleotides are required in order to replicate DNA in the developing germline. Here, Chi and colleagues (pp. 307–320) have used Caernohabditis elegans to identify a GLP-1-dependent checkpoint that senses food (bacterially)-supplied nucleotide levels, arresting reproductive development in the absence of sufficient nucleotide supplies. Cold Spring Harbor Laboratory Press 2016-02-01 /pmc/articles/PMC4743054/ /pubmed/26833726 http://dx.doi.org/10.1101/gad.276980.115 Text en © 2016 Shi and Murphy; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Outlook
Shi, Cheng
Murphy, Coleen T.
Feeding the germline
title Feeding the germline
title_full Feeding the germline
title_fullStr Feeding the germline
title_full_unstemmed Feeding the germline
title_short Feeding the germline
title_sort feeding the germline
topic Outlook
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743054/
https://www.ncbi.nlm.nih.gov/pubmed/26833726
http://dx.doi.org/10.1101/gad.276980.115
work_keys_str_mv AT shicheng feedingthegermline
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