The evolutionary turnover of recombination hot spots contributes to speciation in mice

Meiotic recombination is required for the segregation of homologous chromosomes and is essential for fertility. In most mammals, the DNA double-strand breaks (DSBs) that initiate meiotic recombination are directed to a subset of genomic loci (hot spots) by sequence-specific binding of the PRDM9 prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Smagulova, Fatima, Brick, Kevin, Pu, Yongmei, Camerini-Otero, R. Daniel, Petukhova, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743057/
https://www.ncbi.nlm.nih.gov/pubmed/26833728
http://dx.doi.org/10.1101/gad.270009.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743057/
https://www.ncbi.nlm.nih.gov/pubmed/26833728
http://dx.doi.org/10.1101/gad.270009.115

Ejemplares similares