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Effect of late sodium current inhibition on MRI measured diastolic dysfunction in aortic stenosis: a pilot study

BACKGROUND: Ranolazine is a new anti-anginal drug that acts via late sodium current inhibition, and has been shown to improve diastolic dysfunction in isolated myocytes. Diastolic dysfuntion is common in patients with aortic stenosis (AS), and precedes symptom development and systolic dysfunction. T...

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Detalles Bibliográficos
Autores principales:	Singh, Anvesha, Steadman, Christopher D., Khan, Jamal N., Reggiardo, Giorgio, McCann, Gerry P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743087/ https://www.ncbi.nlm.nih.gov/pubmed/26847571 http://dx.doi.org/10.1186/s13104-016-1874-0

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