Significance of the urokinase-type plasminogen activator and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models

BACKGROUND: suPAR biomarker generally considered a pathogenic factor in FSGS. However, studies have been published that dispute this conclusion. The current study was designed to investigate the roles of uPA and suPAR in FSGS in clinical and mouse models. METHODS: Clinical subjects including those w...

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Detalles Bibliográficos
Autores principales: Chen, Jin-Shuen, Chang, Li-Chien, Wu, Chung-Ze, Tseng, Tzu-Ling, Lin, Jui-An, Lin, Yuh-Feng, Cheng, Chao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743092/
https://www.ncbi.nlm.nih.gov/pubmed/26846181
http://dx.doi.org/10.1186/s12929-016-0242-7

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