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Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743162/ https://www.ncbi.nlm.nih.gov/pubmed/26846095 http://dx.doi.org/10.1186/s13256-015-0778-2 |
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author | Vera-Aguilera, Jesus Mukarram, Osama Nutalapati, Prathibha Mok, Mary Bulumulle, Anushi Vera-Aguilera, Carlos |
author_facet | Vera-Aguilera, Jesus Mukarram, Osama Nutalapati, Prathibha Mok, Mary Bulumulle, Anushi Vera-Aguilera, Carlos |
author_sort | Vera-Aguilera, Jesus |
collection | PubMed |
description | BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene. CONCLUSIONS: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene. |
format | Online Article Text |
id | pubmed-4743162 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-47431622016-02-06 Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature Vera-Aguilera, Jesus Mukarram, Osama Nutalapati, Prathibha Mok, Mary Bulumulle, Anushi Vera-Aguilera, Carlos J Med Case Rep Case Report BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene. CONCLUSIONS: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene. BioMed Central 2016-02-04 /pmc/articles/PMC4743162/ /pubmed/26846095 http://dx.doi.org/10.1186/s13256-015-0778-2 Text en © Vera-Aguilera et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Case Report Vera-Aguilera, Jesus Mukarram, Osama Nutalapati, Prathibha Mok, Mary Bulumulle, Anushi Vera-Aguilera, Carlos Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title | Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title_full | Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title_fullStr | Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title_full_unstemmed | Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title_short | Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
title_sort | bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743162/ https://www.ncbi.nlm.nih.gov/pubmed/26846095 http://dx.doi.org/10.1186/s13256-015-0778-2 |
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