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Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature

BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We...

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Autores principales: Vera-Aguilera, Jesus, Mukarram, Osama, Nutalapati, Prathibha, Mok, Mary, Bulumulle, Anushi, Vera-Aguilera, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743162/
https://www.ncbi.nlm.nih.gov/pubmed/26846095
http://dx.doi.org/10.1186/s13256-015-0778-2
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author Vera-Aguilera, Jesus
Mukarram, Osama
Nutalapati, Prathibha
Mok, Mary
Bulumulle, Anushi
Vera-Aguilera, Carlos
author_facet Vera-Aguilera, Jesus
Mukarram, Osama
Nutalapati, Prathibha
Mok, Mary
Bulumulle, Anushi
Vera-Aguilera, Carlos
author_sort Vera-Aguilera, Jesus
collection PubMed
description BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene. CONCLUSIONS: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene.
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spelling pubmed-47431622016-02-06 Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature Vera-Aguilera, Jesus Mukarram, Osama Nutalapati, Prathibha Mok, Mary Bulumulle, Anushi Vera-Aguilera, Carlos J Med Case Rep Case Report BACKGROUND: Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients. CASE PRESENTATION: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene. CONCLUSIONS: We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene. BioMed Central 2016-02-04 /pmc/articles/PMC4743162/ /pubmed/26846095 http://dx.doi.org/10.1186/s13256-015-0778-2 Text en © Vera-Aguilera et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Vera-Aguilera, Jesus
Mukarram, Osama
Nutalapati, Prathibha
Mok, Mary
Bulumulle, Anushi
Vera-Aguilera, Carlos
Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title_full Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title_fullStr Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title_full_unstemmed Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title_short Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
title_sort bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743162/
https://www.ncbi.nlm.nih.gov/pubmed/26846095
http://dx.doi.org/10.1186/s13256-015-0778-2
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