Characterization of chromatin accessibility with a transposome hypersensitive sites sequencing (THS-seq) assay

Chromatin accessibility captures in vivo protein-chromosome binding status, and is considered an informative proxy for protein-DNA interactions. DNase I and Tn5 transposase assays require thousands to millions of fresh cells for comprehensive chromatin mapping. Applying Tn5 tagmentation to hundreds...

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Detalles Bibliográficos
Autores principales: Sos, Brandon Chin, Fung, Ho-Lim, Gao, Derek Rui, Osothprarop, Trina Faye, Kia, Amirali, He, Molly Min, Zhang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743176/
https://www.ncbi.nlm.nih.gov/pubmed/26846207
http://dx.doi.org/10.1186/s13059-016-0882-7

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