Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice

BACKGROUND: Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condition to the one-carbon metabolism. Thus, the objective was to investigate regula...

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Detalles Bibliográficos
Autores principales: Berge, Rolf K., Bjørndal, Bodil, Strand, Elin, Bohov, Pavol, Lindquist, Carine, Nordrehaug, Jan Erik, Svardal, Asbjørn, Skorve, Jon, Nygård, Ottar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743328/
https://www.ncbi.nlm.nih.gov/pubmed/26846427
http://dx.doi.org/10.1186/s12944-016-0192-9

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